liver transplant bowel cancer
Liver transplantation for bowel (colorectal) cancer with metastases to the liver is a highly specialized and rare treatment approach. Typically, colorectal cancer metastases to the liver are managed with systemic therapies like chemotherapy, targeted therapies, and sometimes surgical resection of liver metastases. Liver transplants are only considered in unique cases, primarily for patients who have unresectable liver metastases but no evidence of cancer outside the liver. Clinical trials, such as those conducted in Norway, have shown that carefully selected patients may benefit from a liver transplant, with improved survival rates in some cases. However, this remains an experimental approach and is not widely adopted due to significant risks and challenges. The primary challenges associated with liver transplants in metastatic bowel cancer include a high risk of cancer recurrence and the need for lifelong immunosuppression after transplantation. Immunosuppressive drugs, while necessar...